Alzheimer is the most common category of Dementia. It is a chronic neurodegenerative disorder and caused by brain cell death. The symptoms of brain cell death are memory loss, disorientation and cognitive decline. The size of the brain shrinks and the nerve cells and attachments in the tissues progressively reduced, which cannot be diagnosed in the living brain affected by Alzheimer's disease, post- mortem/autopsy will always show tiny inclusions in the nerve tissues, called as plaques and tangles. Plaques are found between the dying cells in the brain - from the build-up of a protein called Beta-amyloid (amyloid plaques). The tangles exist in the brain neurons, from the disintegration of the second protein, called Tau. There are no existing treatments or preventive measures to stop or cure Alzheimer’s. Most of the patients with Alzheimer’s are above 65 years of age but 4-5% cases are of early onset Alzheimer’s.
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